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Bookshelf Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. 2022 Sep-Oct;40(5):586-590. doi: 10.1016/j.clindermatol.2022.01.002. Unauthorized use of these marks is strictly prohibited. doi: 10.1111/jdv.17342, 5. This rash is thought to be caused by a virus. J Med Virol 2021; 93: 18501851. Bethesda, MD 20894, Web Policies Keywords: Disseminated erythematous-papulosquamous lesions, with right laterocervical herald patch (clinical aspect on admission). Dermatol Ther. Unauthorized use of these marks is strictly prohibited. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. We present a case of a pityriasis rosea-like rash occurring after Pfizer COVID-19 vaccination and review cases of pityriasis rosea (PR)/PR-like eruption (PR-LE) after mRNA COVID-19 vaccine published in the medical literature. Careers. This site needs JavaScript to work properly. "However, it's possible to develop the rash more than once," she says. (2021) 60:11501. -, Recalcati S. Cutaneous manifestations in COVID-19: a first perspective. Among the common cutaneous manifestations of COVID-19 (e.g., morbilliform eruptions, chilblains, and varicella-like vesicles), PR and PR-like eruptions have rarely been described (6, 7). Among patients who received COVID-19 vaccines, PR-like eruptions have been reported following the first (n = 1) or second dose (n = 2) of BNT162b2 mRNA-based vaccines (3, 4). PR is a common self-limited papulosquamous eruption typically presenting with a large solitary pink-colored patch or plaque (i.e., herald patch), followed by secondary eruptions of smaller erythematous patches or plaques with associated peripheral collarette scaling distributed along the cleavage lines of the trunk, forming a Christmas tree pattern (5). 2021 Aug;35(8):e491-e493. The .gov means its official. A case of Pityriasis rosea is presented in a 66-year-old black male 1 week after administration of the Pfizer-BioNTech COVID-19 vaccine. "Any type of stress on the body can sometimes [cause them, and] any vaccine, not just the COVID one.". The papulovesicular and pityriasis rosea . Patient concerns: We present the case of a female patient in whom the diagnosis of pityriasis rosea led to the investigation and diagnosis of the SARS-CoV-2 infection. How do dermatologists treat pityriasis rosea? Keywords: Treatment with topical 0.1% triamcinolone acetonide twice per day showed partial response after seven days. To the best of our knowledge, there have been no reports of PR-like eruptions following inoculation with Oxford/AstraZeneca ChAdOx1 nCoV-19 (AZD1222) vaccine. One case of pityriasis rosea is reported in a patient infected with COVID-19, and the most commonly reported features are exanthomatous rash, urticaria, chickenpox like vesicles, petechiae, and acute hemorrhagic edema of infancy. Get more info about other skin conditions: The Ultimate Guide to Skin Conditions for Black & Brown Folks, I Thought I Just Had Dry Skin, But It Was Actually Perioral Dermatitis, Everything You Should Know About Hidradenitis Suppurativa. Cutaneous reactions after COVID-19 vaccination in Turkey: A multicenter study. Cutis. The most commonly reported features . In: Jameson J, Fauci AS, Kasper DL, et al., eds. Please enable it to take advantage of the complete set of features! See this image and copyright information in PMC. Front. Unauthorized use of these marks is strictly prohibited. Pityriasis rosea is a benign inflammatory rash that starts with a single red rash, also known as the "herald patch," which eventually gives way to a larger, similar-looking rash on the trunk. Various mild and benign cutaneous manifestations of the different forms of the COVID-19 vaccine have been documented. Epub 2021 Apr 7. Keywords: adverse effect, coronavirus, cutaneous eruptions, immunization, pityriasis rosea, SARS-CoV-2, vaccine, case report, Citation: Leerunyakul K, Pakornphadungsit K and Suchonwanit P (2021) Case Report: Pityriasis Rosea-Like Eruption Following COVID-19 Vaccination. Marcantonio-Santa Cruz OY, Vidal-Navarro A, Pesqu D, Gimnez-Arnau AM, Pujol RM, Martin-Ezquerra G. J Eur Acad Dermatol Venereol. COVID-19-associated pityriasis rosea in children: Case report and literature review. The papillary dermis shows melanin incontinence, perivascular lymphocytic infiltrate and rare scattered extravasated red blood cells. You cant spread pityriasis rosea to another person through unprotected sex or skin-to-skin contact. PMC 2021 Sep;60(9):1150-1151.doi: 10.1111/ijd.15700. While home remedies are safe for most people, its a good idea to check with your healthcare provider before trying some of the following options. Recurrent and persistent pityriasis rosea: an atypical case presentation. Pityriasis Rosea-like eruptions following COVID-19 mRNA-1273 vaccination: A case report and literature review. In: Knoop KJ, Stack LB, Storrow AB, et al., eds. Leerunyakul K, Pakornphadungsit K, Suchonwanit P. Front Med (Lausanne). I also had to stop working out and hiking for about a week, as Alexiades is right excessive perspiration worsened the itch. J Eur Acad Dermatol Venereol. Bin Rubaian NF, Almuhaidib SR, Aljarri SA, Alamri AS. The .gov means its official. official website and that any information you provide is encrypted "Like a lot of things in dermatology, unfortunately, we're not always sure what causes these rashes," says Lam. Disclaimer. Epub 2022 Jun 26. and transmitted securely. Got an extremely itchy rash that came seemingly out of nowhere? 8 In some cases, antibodies against HHV6/7 as well as viral DNA in plasma and PBMCs were detected. One case of pityriasis rosea is reported in a patient infected with COVID-19, and the most commonly reported features are exanthomatous rash, urticaria, chickenpox like vesicles, petechiae, and acute hemorrhagic edema of infancy. Figure 3. The mechanisms behind these COVID-19-related symptoms remain unclear. Epub 2022 Jun 21. PR also tends to occur in patients between the ages of 10 to 35 that are usually otherwise healthy, Lam says. Abdullah L, Hasbani D, Kurban M, Abbas O. Pityriasis rosea after mRNA COVID-19 vaccination. The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding author/s. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753512/), Visitation, mask requirements and COVID-19 information, sexually transmitted disease or infection. 2022 Jan;114:88-89. doi: 10.1016/j.ijid.2021.10.055. Once its gone, you likely wont develop it again. Is there a prescription cream or ointment that you can prescribe? doi: 10.1159/000517971. Involvement of the oral mucosa has also been reported in as many as 50% of all cases (11). Int J Dermatol. 2022 Sep-Oct;40(5):586-590. doi: 10.1016/j.clindermatol.2022.01.002. The condition is more prevalent in spring and fall. Epub 2020 Nov 20. The .gov means its official. Curr Dermatol Rep. 2022;11(4):289-312. doi: 10.1007/s13671-022-00370-9. Parakeratosis with minimal acanthosis and spongiosis of the epidermis. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. J Eur Acad Dermatol Venereol. eCollection 2022. Authors Jordan E Buckley 1 , Laura N Landis 2 , Ronald P Rapini 1 Affiliations Pityriasis rosea isnt a sexually transmitted disease or infection (STD or STI). Bookshelf Pityriasis rosea commonly affects the skin on your trunk, arms or legs. "Other treatments including phototherapy or oral medications can be considered for extensive or persistent cases, [and] some small case studies support the use of oral antivirals like acyclovir or oral anti-inflammatory antibiotics erythromycin," King explains. Herein, we are reporting a unique. Accessibility Chanprapaph K, Pomsoong C, Tankunakorn J, Eden C, Suchonwanit P, Rutnin S. Comparative analyses of clinical features, histopathology, and CD123 immunohistochemistry of oral lupus erythematosus, lichen planus, and other lichenoid lesions. doi: 10.1111/jdv.12942, 13. Federal government websites often end in .gov or .mil. Zendaya Shows Off Her Short Sunshine Curls. I video-chatted with my dermatologist who asked a few questions: Did I have body aches or flu-like symptoms? The good news is many of those who develop pityriasis rosea never get it again, says New York City-based dermatologist Hadley King. (No.) Clin Dermatol. Before Dermatol Ther. It may appear on any part of your body, but it usually appears on the trunk (torso), arms and legs. Our experience with 80 cases of SARS-CoV-2-Clostridioides difficile co-infection: An observational study. Cutaneous Reactions Following COVID-19 Vaccination: A Review of the Current Literature. In approximately 50% of people with pityriasis rosea, the patches itch. J Eur Acad Dermatol Venereol 2020;34:e4367. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). Some treatments can alleviate related symptoms, including itching. In darker-skinned or Black people, the patches may be more raised (papular), and the centers of the patches may look like the tissue is dying (necrotic). (b) haematoxylineosin, original magnification 20. However, the studies dont conclusively prove that COVID-19 causes pityriasis rosea. Lastly, Hartman says PR can present differently in patients with darker skin: "The characteristic erythematous plaques may appear more hyperpigmented or violaceous in darker skin types. For most people, it resolves without treatment. Lessons: Although histopathologic characteristics of PR are also observed in PR-like lesions, the presence of dyskeratotic keratinocytes, interface dermatitis, and eosinophilic infiltration in the dermis may be more prominent in PR-like eruptions (11). 8600 Rockville Pike doi: 10.1111/bjd.20143. Due to the rising incidence of coronavirus disease 2019 (COVID-19) worldwide, mass vaccination has been the cornerstone in preventing viral spread and decreasing morbidity and mortality. It is likely that a new viral trigger of pityriasis rosea is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). official website and that any information you provide is encrypted -, Busto-Leis J.M., Servera-Negre G., Mayor-Ibarguren A., et al. Would you like email updates of new search results? Borgia F, Li Pomi F, Alessandrello C, Vaccaro M, Pioggia G, Gangemi S. J Dermatol. Epub 2021 May 10. Histopathological findings of pityriasis rosealike eruption in patient 1. -, Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 vaccine. JAAD Case Rep. (2018) 4:8001. According to King, an in-person skin exam is usually enough to make an accurate diagnosis, though a biopsy or blood work may be necessary for some. Human herpesvirus-6, -7, and Epstein-Barr virus reactivation in pityriasis rosea during COVID-19. National Library of Medicine Refined carbohydrates, such as sugar, pastries and white bread. eCollection 2022. Accessibility However, a fungus causes ringworm. Epub 2022 Jun 14. Federal government websites often end in .gov or .mil. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. Adverse cutaneous reactions following COVID-19 vaccines have increased, highlighting not only how SARS-CoV-2 infection but also COVID-19 vaccines may induce adverse cutaneous manifestations.